Genetic deletion or tyrosine phosphatase inhibition of PTPRZ1 activates c-Met to up-regulate angiogenesis and lung adenocarcinoma growth.

Pinelopi Kastana, Despoina Ntenekou, Eleni Mourkogianni, Michaela-Karina Enake, Athanasios Xanthopoulos, Effrosyni Choleva, Antonia Marazioti, Sophia Nikou, Racheal G Akwii, Eleni Papadaki, Esther Gramage, Gonzalo Herradón, Georgios T Stathopoulos, Constantinos M Mikelis, Evangelia Papadimitriou

Int J Cancer. 2023 Sep 1;153(5):1051-1066. doi: 10.1002/ijc.34564. Epub 2023 Jun 1.PMID: 37260355

Implication of the PTN/RPTPβ/ζ Signaling Pathway in Acute Ethanol Neuroinflammation in Both Sexes: A Comparative Study with LPS.

Rodríguez-Zapata M; Galán-Llario M; Cañeque-Rufo H; Sevillano J; Sánchez-Alonso MG; Zapico JM; Ferrer-Alcón M; Uribarri M; Pascual-Teresa Bd; Ramos-Álvarez MdP; Herradón G, Pérez-García C; Gramage E.

Biomedicines. 2023 Apr 28;11(5):1318. doi: 10.3390/biomedicines11051318. PMID: 37238989; PMCID: PMC10215719.

Pleiotrophin deficiency protects against high-fat diet-induced neuroinflammation: Implications for brain mitochondrial dysfunction and aberrant protein aggregation. 

Cañeque-Rufo H, Sánchez-Alonso MG, Zuccaro A, Sevillano J, Ramos-Álvarez MDP, Herradón G.

Food Chem Toxicol. 2023 Feb;172:113578. doi: 10.1016/j.fct.2022.113578. Epub 2022 Dec 23. PMID: 36566969.

Receptor protein tyrosine phosphatase β/ζ regulates loss of neurogenesis in the mouse hippocampus following adolescent acute ethanol exposure.

Galán-Llario M, Rodríguez-Zapata M, Gramage E, Vicente-Rodríguez M, Fontán-Baselga T, Ovejero-Benito MC, Pérez-García C, Carrasco J, Moreno-Herradón M, Sevillano J, Ramos-Álvarez MP, Zapico JM, de Pascual-Teresa B, Ramos A, Herradón G.

Neurotoxicology. 2023 Jan;94:98-107. doi: 10.1016/j.neuro.2022.11.008. Epub 2022 Nov 17.PMID: 36402194

Inhibition of RPTPβ/ζ reduces chronic ethanol intake in adolescent mice and modulates ethanol effects on hippocampal neurogenesis and glial responses in a sex-dependent manner.

Galán-Llario M, Rodríguez-Zapata M, Fontán-Baselga T, Gramage E, Vicente-Rodríguez M, Zapico JM, de Pascual-Teresa B, Lasek AW, Herradón G.

Neuropharmacology. 2023 Jan 24;227:109438. doi: 10.1016/j.neuropharm.2023.109438. Online ahead of print.PMID: 36706907


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